Development and Verification of CTX Imaging for Musculoskeletal Biomechanics Research
This team, composed of zoologists, bioengineers and a computer scientist, is collaborating on the development of “CTX,” a new biomedical imaging technology for dynamic visualization of bones and joints in motion. With this advanced technology researchers will be able to look inside living humans and animals and see their skeletons moving in 3D. This new technology will find broad application in orthopedics and zoological biomechanics research, and possibly lead to clinical diagnosis and treatment of orthopedic problems.
PI: Elizabeth Brainerd, Professor, Ecology and Evolutionary Biology
Co-PIs: Joseph J. Crisco, Associate Professor, Orthopedics; Braden C. Fleming, Associate Professor, Orthopedics; Stephen M. Gatesy, Associate Professor, Ecology and Evolutionary Biology; David H. Laidlaw, Associate Professor, Computer Science; Douglas C. Moore, Associate Director of Bioengineering Laboratory, Orthopedics; Thomas J. Roberts, Assistant Professor, Ecology and Evolutionary Biology; Sharon M. Swartz, Associate Professor, Ecology and Evolutionary Biology
$100,000
Nanoscale Biomimetic Materials for Nerve Regeneration
The goal of this project is to determine the critical cues needed to guide nerves, thus providing essential information for new strategies for nerve regeneration. This interdisciplinary team from Molecular Pharmacology, Physiology and Biotechnology and the Division of Engineering, hopes to converge synergistically to develop and fabricate novel biomimetic biomaterial systems with drug delivery capabilities, to characterize these biomaterials in vitro, and to evaluate them in in vivo models of nerve injury.
PI: Diane Hoffman-Kim, Assistant Professor, Molecular Pharmacology, Physiology and Biotechnology
Co-PIs: Thomas Webster, Associate Professor, Engineering; Edith Mathiowitz, Professor, Molecular Pharmacology, Physiology and Biotechnology; Moses Goddard, Associate Professor (Research), Molecular Pharmacology, Physiology and Biotechnology
$98,727
Exceptional Children—Exceptional Challenges: Developing an Interdisciplinary, Multinational Project for Studying Work-Family Dilemmas among Parents Raising Children
This team of sociologists, along with an economist and pediatrician, will undertake an innovative pilot study to gather preliminary research on the prevalence and types of child disability, the choices families make to meet conflicting family economic needs and time constraints, and the relative public and private costs of raising children with disabilities. The emphasis will be on the analyses that contrast and compare varying societies, starting with a U.S.-Australia comparison analysis of work/family dilemma.
PI: Dennis P. Hogan, Professor, Sociology
Co-PIs: Anna Aizer, Assistant Professor, Economics; Peter D. Brandon, Adjunct Associate Professor, Populations Studies and Training Center, and Australian Professorial Fellow and Professor of Demography and Sociology, Research School of Social Sciences, the Australian National University; Patrick Heller, Associate Professor, Sociology; Michael E. Msall, Professor of Pediatrics, Pritzker School of Medicine, University of Chicago; Susan Short, Associate Professor, Sociology
$81,654
Structural Biology and Function of Macromolecular Complexes. Using Dynamic Light Scattering to Initiate the Establishment of a Brown University Facility for State-of-the-Art Biophysical Protein Characterization
This undertaking will add essential instrumentation to the cross-disciplinary and inter-disciplinary Laboratories of Molecular Medicine (LLM), which is home to a diverse set of faculty whose research interests span all levels of biology. The acquisition of a dynamic light scattering (DLS) instrument will facilitate key collaborative research studies of eight primary uses and help to establish a centralized facility for protein biophysical characterization.
PIs: Rebecca Page, Assistant Professor, Molecular Biology, Cell Biology and Biochemistry and Gerwald Jogl, Assistant Professor, Molecular Biology, Cell Biology and Biochemistry
Co-PIs: Laurent Brossay, Assistant Professor, Molecular Microbiology and Immunology; Albert E. Dahlberg, Professor, Molecular Biology, Cell Biology and Biochemistry; David E. Cane, Professor, Chemistry; Dale F. Mierke, Associate Professor, Molecular Pharmacology, Physiology and Biotechnology; Wolfgang S. Peti, Assistant Professor, Molecular Pharmacology, Physiology and Biotechnology; Anatoly Zhitkovich, Associate Professor, Pathology and Laboratory Medicine
$53,074
Brown Influenza Microchip: Rapid Identification of Sequence Specific Subtypes
In this project, the Division of Engineering teams up with Medical School faculty to develop an Influenza Detection Microchip capable of rapidly identifying influenza subtypes, which is not currently possible outside of specialized labs. This new technology aims to provide health care and public health professionals with key information for determining a public health response appropriate to the viral threat.
PI: Anubhav Tripathi, Assistant Professor, Engineering
Co-PIs: Andrew W. Artenstein, Associate Professor, Medicine; Steven M. Opal, Professor, Medicine
$99,944
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