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Chemistry, Department of

Brown Faculty
30 matches found.

 James Baird
Chemistry, Department of
There is a great interest in understanding processes occurring in the ground and excited states of both atoms and molecules. Professor Baird's research in chemical physics involves studies of energy and state transfer collisions, as well as measurement of energy level separations, in simple molecular and atomic species. For example, in studying the resonance fluorescence from atomic thallium it has been possible to measure the free atomic lifetime, radiation trapping (coherent narrowing), the resonance collision cross sections caused by rare gas thallium collisions. Also in these studies there is evidence of multiple collisions in the excited state-ground state atoms.
 Amit Basu
Chemistry, Department of
Our group is interested in questions that lie at the interface of chemistry, biology, and materials science. Research in the group includes –glycochemistry and glycobiology; synthesis and application of novel polymers and nanomaterials; development of new sensors and diagnostic agents.
 Carthene R. Bazemore-Walker
Chemistry, Department of
BIOANALYTICAL CHEMISTRY
We seek to identify biomarkers of disease and to define disease mechanisms at the molecular level by utilizing tools of analytical chemistry, specifically high resolution chromatography and state of the art mass spectrometry.
 Wesley Bernskoetter
Chemistry, Department of
Research in the Bernskoetter lab focuses on the use of inorganic and organometallic complexes to address challenges relevant to our planet's growing energy concerns. Our initiatives employ techniques from synthetic organic and inorganic chemistry to study highly reactive molecules capable of mediating difficult chemical transformations.
 David Cane
Chemistry, Department of
The main focus of Professor Cane's research has been to establish the mechanism of formation of a wide variety of naturally occurring substances of diverse biological origins. These metabolites include antibiotics, toxins, plant defense substances, essential oils, and vitamins. Over the last several years his research group has concentrated on the mechanistic enzymology and molecular genetics of two broad areas, terpenoid metabolism and polyketide antibiotic biosynthesis.
 Ruggero Curci
Chemistry, Department of
Our studies are directed toward investigating the properties and the reactivity of new peroxide species which allow selective oxidations. In recent times, our efforts have focused on a new class of reactive organic peroxides that are powerful oxidants and have great potential for synthetic purposes.
 Sarah Delaney
Chemistry, Department of
The research in my laboratory aims to understand the biological consequences of DNA damage. Using the tools of chemistry and biology we probe the effects of DNA modification at the molecular level. We are particularly interested in the role of oxidative DNA damage and its contributions to cancer and neurological disorders such as Huntington's disease.
 Gerald Diebold
Chemistry, Department of
The process of sound wave generation by light, known as the photoacoustic effect, is quite general and can be initiated in liquids and solids as well as gases. The Diebold group has focused on photoacoustic research for the last two decades, investigating fundamental phenomena and new effects. Much of the current effort in the group has been devoted to transient grating experiments, a photoacoustic recording method that has high time resolution. The most recent research directions for the Diebold group have been x-ray phase contrast imaging and imaging with the ultrasonic vibration potential. The latter is a completely new imaging modality.
 Jimmie Doll
Chemistry, Department of
The study of complex, many-body chemical phenomena has entered a new and exciting phase. Novel theoretical approaches are emerging that make it possible to examine systems of chemically significant complexity without invoking untestable approximations. Our investigations involve both the formal development and numerical application of these methods.
 Kathleen Hess
Chemistry, Department of
 Hannes Jonsson
Chemistry, Department of
The rapid advance in computers continues to open up new and exciting research possibilities in computational science. In the Jonsson group, theoretical methods are being developed and applied to computational studies of condensed matter to learn about the properties of liquids, crystals and amorphous solids in terms of the electronic wavefunctions and the atomic ordering and dynamics. Surfaces and interfaces have been a particular focus including the interaction of atoms and molecules with surfaces of solids. For more information, see http://www.hi.is/~hj/researchprojects.html
 Eunsuk Kim
Chemistry, Department of
The research projects in the Kim lab are in the area of bioinorganic chemistry with a goal of developing fundamental inorganic chemistry to address challenging biological and environmental problems and questions. Toward this goal, our research program will use a multidisciplinary approach, drawing from synthetic inorganic chemistry, spectroscopy, biochemistry, and toxicology.
 Joan Lusk
Chemistry, Department of
 John Oliver
Chemistry, Department of
A recent effort in our lab is a collaboration with colleagues in the Chemistry Department (Kathlyn Parker and William J. Suggs) and in the Computer Science Department (Eli Upfal and Franco Preparata). We are investigating the behavior of synthetic and natural nucleosides in DNA hybridization experiments. Our goal is to find a ""universal"" base with particular characteristics that will allow us to use gapped or patterned probes for Sequencing By Hybridization (SBH). When used for SBH, gapped probes will increase the information content of oligonucleotide based microarrays by at least 100-fold and will lower the cost of DNA sequencing.
 Wolfgang Peti
Molecular Pharmacology, Physiology and Biotechnology, Department of
Chemistry, Department of
The focus of my research group is to understand the molecular basis of PP1 regulation. We combine the information derived from biomolecular NMR spectroscopy, X-ray crystallography, and additional biophysical techniques, such as ITC, DSC, Biacore, and CD spectroscopy to undertsand how PP1 is targeted, regulated and inhibited in vitro and in vivo. Furthermore, my research group is pursuing the production and the structure elucidation of membrane proteins and protein essential for the formation of bacterial biofilms.
 G. Satya Reddy
Chemistry, Department of
 William Risen
Status: Emeritus
Chemistry, Department of
Our group conducts research in the following areas: Aerogel Chemistry, Inorganic Glasses, Bioinorganic Polymers, Chemical and Physical Properties of Ionomers, Polyurethane Ionomer Chemistry, and Ionomers in Fuel Cells.
 Christoph Rose-Petruck
Chemistry, Department of
The ultrafast motions of atoms during chemical reactions are investigated theoretically and experimentally using x-ray absorption fine structure spectroscopy.
Physical processes, such as the propagation of shock waves in metals, are measured using ultrafast x-ray holography.
Biomedical x-ray phase contrast imaging studies of the micro vasculature of livers are performed.
X-ray phase contrast imaging of organs during ultrasound irradiation is used to selectively enhance organ tissue featrues.
 Sandra Russo-Rodriguez
Chemistry, Department of
 Jason Sello
Chemistry, Department of
My research is inspired by naturally occurring antibiotics and the organisms from which they come. Streptomyces bacteria and their antibiotics are the primary subjects of my research. These soil-dwelling bacteria produce half of the 10,000 known antibiotics and about two-thirds of the medicinal natural products (e.g. FK506, tetracycline, daptomycin, and doxorubicin.) My interests are the molecular mechanisms in Streptomyces bacteria that underly the production of and resistance to antibiotics.
 Christopher Seto
Chemistry, Department of
Our research interests are aimed toward investigating and manipulating the noncovalent interactions that govern molecular recognition in biological systems. We are studying interactions between proteins and their ligands, between proteins and DNA, and the noncovalent interactions that dictate protein secondary and tertiary structure. These projects utilize traditional tools of organic chemistry such as synthesis and spectroscopic evaluation of molecular structure and conformation, and also employ a variety of more biological techniques such as electrophoresis, enzymology, and protein isolation and purification.
 Joseph Steim
Status: Emeritus
Chemistry, Department of
Phospholipids play a crucial role in the architecture of biological membranes as well as in many biochemical processes. This structural role of phospholipid molecules reflect their physical properties, which are determined by their peculiar ability to self-assemble into a variety of supramolecular assemblies, including the well-known phospholipid bilayers present in every living cell of every organism. The understanding of the properties of the phospholipids has benefited immensely from such techniques as NMR and calorimetry, and in our laboratories we apply these and other physical methods to further clarify the physical chemistry of lipids and the biomembranes made from them.
 Richard Stratt
Chemistry, Department of
The prospects for making sense of dynamics in liquids have improved dramatically in the recent years. With the advent of ultrafast lasers has come the ability to look at times short enough that the painful complications have barely begun to set in. Our own work has been focused on developing a theoretical understanding of this ultrafast dynamics. In particular, we are hoping to discern the molecular mechanisms of events such as solvation and vibrational relaxation -- the elementary steps that determine the course of chemical reactions in liquids.
 J. William Suggs
Chemistry, Department of
Keywords: Bioorganic, organometallic, chemical communication
 Shouheng Sun
Chemistry, Department of
Professor Sun's research in nanomaterials involves two related areas: (1) chemical synthesis and self-assembly of nanoparticles; (2) construction and elaboration of functional nanoparticles and their assemblies for applications in biomedicine, catalysis, and information storage.
 Dwight Sweigart
Chemistry, Department of
The Sweigart group does research in organometallic chemistry. Current work is focused in three major areas: electrochemistry, self-assembly, and catalysis.
 Lai-Sheng Wang
Chemistry, Department of
 Peter Weber
Chemistry, Department of
Our research explores fundamental molecular processes in the broadest sense. We have developed two highly time-resolved techniques to explore molecular dynamics from two different perspectives. In the first experiment, a pump-probe photoelectron spectroscopy technique allows us to observe the flow of energy in molecules. The second experiment follows structural rearrangements by a time-resolved diffraction technique. The spectroscopic and the structural measurements are complementary, and combining them leads to a better understanding of molecular reactions.
 Paul Williard
Chemistry, Department of
Paul Williard works in the area of organic synthesis. His research topics include: X-Ray crystal structure determination of intermediates for organic synthesis; total synthesis of physiologically active compounds; and development of synthetic methodology.
 Matthew Zimmt
Chemistry, Department of
Research program: 1. Functional Architectures for Control of Electron Transfer at Electrodes 2. Molecular Test Bridges for Studies of Electron Tunneling. 3. Optical Screeing Methods for Library Evaluation in Microarrays 4. Probing Weak Interactions Between Bio-molecules Using a Fluorescence Balance.

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