You're searching for faculty members in:
Neuroscience, Department of
31 matches found.
 | Carlos Aizenman
Neuroscience, Department of
My research focuses on the development of the visual system. We use the relatively simple and experimentally tractable visual system of Xenopus laevis tadpoles. By understanding the role that sensory experience plays in the development of this system we will begin to understand the guiding principles by which the brain wires itself up during development. |  | Jennifer Aizenman
Neuroscience, Department of
|  | Gilad Barnea
Neuroscience, Department of
|  | Patrick Bedard
Neuroscience, Department of
|  | David Berson
Neuroscience, Department of
My lab studies what the eye tells the brain. We explore the structure and function of ganglion cells, the retinal neurons that communicate directly with the brain. There are more than a dozen types of ganglion cells. Each has anatomical and physiological features matched to the requirements of specific visual behaviors. We recently discovered a bizarre new type that is a true photoreceptor, responding directly to light like a rod or cone. These cells synchronize the biological clock and constrict the pupil. We seek to understand how these cells work and how their signals are used by the brain. |  | Lucien Bienenstock
Applied Mathematics, Division of
Neuroscience, Department of
Elie Bienenstock studies the mechanisms used by brains to create and compose complex representations. His research, focusing on models of vision, assumes that brains use compositional hierarchies of explicit and detailed representations of objects, parts, and relationships. With colleagues in neuroscience and applied math, he investigates the hypothesis that the fine temporal structure of cortical activity, e.g. the synchronous firing of neurons, plays an important role in these representations. |  | Rebecca Burwell
Psychology, Department of
Neuroscience, Department of
My research program uses neuroanatomical, experimental lesion, and electrophysiological approaches to examine the contribution of brain regions adjacent to the hippocampus (including the perirhinal, postrhinal/parahippocampal, and entorhinal cortices) to memory and to other higher cognitive functions. |  | Barry Connors
Neuroscience, Department of
I study the cellular physiology of the mammalian brain. Most of my work centers on the neocortex, which is responsible for thinking, remembering, processing sensory information, and controlling movement. The neocortex is a vast network of interconnected neurons. My research group studies the properties of these neurons, their synaptic connections, and the characteristics of cortical networks. We are also interested in the mechanisms of epileptic seizures. |  | Scott Cruikshank
Neuroscience, Department of
I study processing mechanisms in sensory thalamus and neocortex, which are brain areas that allow us to sense, perceive, think and learn. This work utilizes several techniques, including electrical recording from neurons in whole animals and in brain slices kept alive under glass. Anatomical and drug studies complement the recording experiments. The goal is to characterize principles of thalamic and neocortical microcircuits and contribute to an overall understanding of brain operation. |  | John Donoghue
Neuroscience, Department of
Our laboratory investigates how the brain turns thought into voluntary behaviors and how that knowledge can be used to help persons with paralysis. We study how populations of neurons represent and transform information as a motor plan becomes movement. This approach has required the creation of a novel recording array to study neural ensembles. With the knowledge we have gained about movement representation, we have translated our findings to a clinical application in which humans with paralysis can use their neurons directly to control devices. |  | Anna Dunaevsky
Neuroscience, Department of
The primary goal of this lab is to elucidate the cellular and molecular mechanisms that underlie the formation, maintenance and modification of synapses in the central nervous system. |  | Justin Fallon
Neuroscience, Department of
Our lab has two major interests. Duchenne muscular dystrophy strikes one in 3,000 boys. We are currently working to translate our basic science findings into a novel treatment for Duchenne's patients.
Second, how do we learn, and why are we so good at it when we are young? Using Fragile X mental retardation as a model, we seek to understand how ephemeral episodes of experience are transformed into stable changes in synaptic architecture and efficacy. | | | Samuel Greenblatt
Neurosurgery
Neuroscience, Department of
Writing an 'intellectual biography' of the English neurologist, John Hughlings Jackson (1835-1911). He (and Charcot in France) set the paradigm for neurological thinking to the present time. I believe he also influenced our fundamental thought patterns in basic neuroscience/neurophysiology through his indirect but strong influence on Sherrington and other British neuroscientists in the 20th century. If we could understand the assumptions in this paradigm, could we do the current science better? |  | Anne Hart
Neuroscience, Department of
Anne Hart is a neurobiologist who uses genetic and molecular approaches in the small nematode C. elegans to understand the conserved mechanisms underlying neurodegenerative disease and nervous system function. She focuses on delineating cellular and molecular pathways pertinent to Huntington's Disease (HD) and Spinal Muscular Atrophy (SMA). Dr. Hart also studies how animals respond to sensory stimuli, adapt to environmental stress, and mechanisms of aging. | | | Seth Horowitz
Neuroscience, Department of
My research focuses on the development, adaptation, and interaction between different sensory systems in aquatic and terrestrial vertebrates. I use behavioral, physiological, anatomical and molecular techniques to explore how animals create and interact with the world of their senses. I've worked with dolphins, bats, rodents, frogs, and the occasional human, and am continually amazed at the similar mechanisms these species use to deal with their radically differing habitats and lifestyles. |  | Diane Lipscombe
Neuroscience, Department of
We study the cellular mechanisms that control the precise architectural features of calcium ion channels in neurons. These mechanisms tell us how voltage-gated calcium ion channels control such a vast and disparate array of neuronal functions. Alternative pre-mRNA splicing fine tunes calcium ion channel structure in specific neurons for optimal performance. Our work addresses basic mechanisms that control calcium channel function in normal as well as in disease states, including chronic pain and mental illness. | | | Jean McElroy Marshall
Neuroscience, Department of
| | | Stefan McDonough
Neuroscience, Department of
|  | James McIlwain
Neuroscience, Department of
|  | Michael Paradiso
Neuroscience, Department of
Humans are highly visual animals and the processing of visual information appears to involve a significant fraction of the brain. Vision involves interactions between neurons spread widely across the brain and it dynamically adapts to the needs of ongoing behavior. The aims of Dr. Paradiso's research are to elucidate the encoding of visual information in cerebral cortex, the computations performed by interacting neurons, and the adaptive use of neural circuitry, with the goal of understanding the mechanisms underlying human visual perception. |  | Robert Patrick
Neuroscience, Department of
Our research is aimed at elucidating how alterations in neurotransmitter activity in the central nervous system influence behavior. We are especially interested in determining how chronic administration of a psychoactive drug, such as amphetamine, alters brain functioning from both a behavioral and transmitter point of view. | | | Mengia-Seraina Rioult-Pedotti
Neuroscience, Department of
|  | Jerome Sanes
Neuroscience, Department of
I study brain mechanisms underlying motor control and learning. Several brain regions, including the frontal and parietal lobes, the basal ganglia, and the cerebellum, have involvement in voluntary movements, and these areas become engaged when humans learn and then consolidate new motor skills. Currently, we study these problems with magnetic resonance imaging technology that assesses focal changes in blood flow and by assessing movement patterns while humans perform various movement tasks. |  | David Sheinberg
Neuroscience, Department of
Research in my lab explores the dynamic nature of sensory processing. In the real world, both the observer and the environment change over time, meaning that the brain must process a dynamic stream of visual information and efficiently parse this information to reach conclusions about the presence or absence of noteworthy objects to which actions should be directed. By studying the activity of neural circuits involved in this process, we aim to better understand mechanisms underlying perception. |  | Andrea Megela Simmons
Psychology, Department of
Neuroscience, Department of
My laboratory studies how the nervous system develops, matures, and reorganizes in response to damage. We use frogs as a model system because these animals go through a lengthy larval stage during which their bodies and brains transform to accommodate the transition from an aquatic to an amphibious lifestyle. As adults, frogs can regenerate damaged cranial nerves, making them excellent models to understand the molecular bases of how the brain might recover from injury. |  | James Simmons
Neuroscience, Department of
I'm interested in understanding how the bat's sonar works and how the bat's brain makes sonar images. They make sounds, listen to echoes, and then see objects. To study echolocation, we go into the field and videotape bats using sonar for different purposes. These observations tell us in what situations bats use their sonar, and what sorts of sounds they use. If we know where the objects are in the videos, we can figure out what sounds get back to the bats. |  | John Stein
Neuroscience, Department of
Outside of teaching and administrative duties at Brown, I have spent a good deal of time over the past eight years participating in science outreach activities in the local community. I am currently collaborating with members of the Brown community and local professionals on an NCRR/NIH Science Education Partnership Award titled Project ARISE: Advancing Rhode Island Science Education. The goal of this project is to develop innovative science instruction in local high school science classrooms. | | | Wilson Truccolo-Filho
Neuroscience, Department of
| | | Edward Walsh
Neuroscience, Department of
Functional magnetic resonance imaging (fMRI) is a powerful tool for the spatial and temporal localization of neuronal activity. My work involves the development and implementation of MRI acquisition and reconstruction techniques that reduce or eliminate difficulties associated with rapid functional acquisitions, including geometric distortion and signal loss in regions of the brain located near air-tissue interfaces, such as the orbitofrontal cortex. |  | Michael Worden
Neuroscience, Department of
Michael Worden's research uses neuroimaging (fMRI, EEG) and behavioral techniques to investigate brain processes involved in attention and visual perception. His interests focus on how attention is influenced by the properties of the items to which attention is directed and the specific mechanisms by which the brain is able to select relevant items and suppress other items. He also investigates how attention is influenced by behavior such as recent experience and extensive practice. | | | Jun Zhuang
Neuroscience, Department of
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